Myasthenia gravis pseudoparalytica is a rare form of muscle weakness. Characteristic of this autoimmune disease is the rapid fatigue of the muscles. Mainly affected by muscle weakness are the eyes and the face.
However, further progression of the disease may also affect other muscle groups, including the heart and lungs. Patients with myasthenia gravis pseudoparalytica have symptoms similar to paralysis.
The causes of myasthenia gravis pseudoparalytica are abnormal neuromuscular transmission, which means that the signals between the muscles and nerves of the affected patient are not properly transmitted.
Myasthenia gravis pseudoparalytica is a disease in which a person's immune system is directed against their own body. Doctors refer to this as an autoimmune disease. In the case of myasthenia gravis pseudoparalytica, this autoimmune reaction interferes with neuromuscular transmission, resulting in faster fatigue of the musculature with the symptoms of paralysis.
However, even if the thymus - a gland in the sternum of the human - due to a disease, such as a malignant tumor, is changed, this may result in a myasthenia gravis pseudoparalytica. The thymus is responsible for controlling the human immune system, which can lead to an autoimmune reaction in a diseased gland.
Approximately 80% of all patients with myasthenia gravis pseudoparalytica suffer from a thymic disorder. However, mental stress situations such as a death or a pregnancy can be the cause of myasthenia gravis pseudoparalytica.
The first signs of myasthenia gravis pseudoparalytica are usually caused by rapid muscle fatigue-related visual disturbances. Typical is the seeing of double images, often loosen the upper eyelids of the eyes on one or both sides and hang down (ptosis). In about 20 percent of patients, the disease is limited to these symptoms, the doctor speaks of a pure ocular myasthenia gravis.
In many cases, however, the disease spreads to other muscle group, in principle, all consciously controllable muscles may be affected. A relatively common paralysis of the facial muscles is accompanied by the loss of facial expressions: striking is the emotionless facial expression of the patient. When the disease spreads to the muscles of the lips, palate, lungs and larynx, speech and swallowing disorders are the result.
An involvement of the respiratory muscles is also possible and manifests itself by increasing shortness of breath: In the worst case, it can come in the context of a myasthenic crisis to a sudden and massive deterioration with acute suffocation. Unintentionally controllable muscles such as the heart muscle are not affected by the disease.
The symptoms of myasthenia gravis pseudoparalytica usually worsen under load. Characteristic is also the dependence on the time of day: The complaints are rather weak in the morning and strengthen significantly by the evening.
To diagnose a myasthenia gravis pseudoparalytica, the affected patient should consult a neurologist. This will first ask the patient in detail about his symptoms and then determine the myasthenia gravis pseudoparalytica with certain neurological tests.
The typical symptoms are in addition to the rapid fatigue of the musculature also visual disturbances, an expressionless facial facial expression, swallowing and speech disorders and heart or lung problems (eg shortness of breath). In addition, a myasthenia gravis pseudoparalytica can be detected by means of various drug tests. These are used to check the neuromuscular signal transmission and the load capacity of the muscles. Electromyography is also commonly used in cases of suspected myasthenia gravis pseudoparalytica.
With the help of this examination the activity and fatigue of the muscle is analyzed. To detect any changes in the thymus gland, most doctors also recommend a CT scan and chest X-ray.
Myasthenia gravis pseudoparalytica is not expected to reduce life expectancy, and the limitations caused by this disease are minor in most patients. However, regular check-ups with the neurologist should be made in order to detect the progression of myasthenia gravis pseudoparalytica in good time.
Due to the myasthenia gravis pseudoparalytica suffer the sufferers of significant restrictions in everyday life. It comes to a very strong fatigue and fatigue of the patient, so that physical activities or sports for the person concerned are no longer possible. Likewise, it is not uncommon for blurred vision, which continue to significantly reduce the quality of life of the person affected.
The affected see blurred or double images, sometimes it comes to the so-called Schleiersehen. The muscles are weak, so it can come to developmental disorders, especially in children. This often leads to social exclusion or mental illness. Muscles on the face are also affected by myasthenia gravis pseudoparalytica, which can cause dysphagia.
Difficulty in swallowing results in more difficulty in taking fluids and food so patients may be underweight or deficient. As a rule, myasthenia gravis pseudoparalytica can not be treated causally. However, the symptoms can be limited with the help of medication, so that the life expectancy of the patient is not reduced. There are no special complications and the development of the child can take place in the usual way.
If the victim suffers from prolonged stress or mental stress, the help and support of a doctor or therapist should be sought. If there is a decrease in physical performance, a weakening of the muscles or everyday obligations can only be perceived to a limited extent, a doctor should be consulted. There is an irregularity that should be followed up with a fast fatigue, an increased sleep requirement as well as an internal weakness. General malady, malaise and visual impairment should be discussed with a physician.
If it comes to the perception of double vision, a blurred vision or an increased risk of accidents and injury, a doctor should be consulted. There is a need for action in the event of disturbances of the vocalization, irregularities in the act of swallowing and abnormalities of the cardiac rhythm. Since in serious cases threatens a life-threatening condition, a doctor's visit should take place as soon as possible at the first sign. Changes in the muscles in the mouth and throat must be presented to a doctor so that there are no sequelae such as loss of appetite or unwanted weight loss.
In case of a respiratory disorder, a complicated breathing activity as well as anxiety a doctor is needed. If an acute condition develops due to respiratory distress, an emergency medical service must be alerted. By the time of arrival, first-aid measures must be taken by those present to ensure the person's survival.
In a myasthenia gravis pseudoparalytica, the neurologist will recommend treatment with medications that suppress the body's immune system (immunosuppressants).
In this way, the symptoms of muscle weakness in most cases can be suppressed very well and also over a longer period of time. Furthermore, cholesterol inhibitors have a positive effect on the disturbed neuromuscular transmission. However, they are not suitable for prolonged use because the effectiveness of these drugs decreases quickly.
In very severe cases, which are responsible for a lesion or tumor of the thymus gland, or in patients under 50, the removal of the thymus gland is often recommended. Even though the symptoms of Myasthenia gravis pseudoparalytica tend to diminish very slowly as a result of the removal, it helps a large number of patients permanently.
Since the symptoms associated with a myasthenia gravis pseudoparalytica can vary greatly in severity and localization, a general prognosis is difficult. However, due to the slow progression in most cases, the prognosis is favorable for early and appropriate therapy. The majority of those treated respond well to treatment.
The complaints are falling back, so that they can lead a largely normal everyday life with only minor physical restrictions. Myasthenia gravis pseudoparalytica also has no negative impact on life expectancy. However, the attending physician controls the course of the disease at regular intervals in order to detect any worsening at an early stage and to be able to order necessary adjustments in the treatment.
Without therapy, on the other hand, the symptoms associated with a myasthenia gravis pseudoparalytica usually worsen. This leads to serious complications. In particular, the respiratory muscles may fail as the disease progresses. Not only is this life threatening and can lead to premature death, but may also require lifelong artificial respiration. For example, earlier than when no modern therapy for the disease existed, about one third of those affected already died in the first years of illness.
There are no effective ways to prevent myasthenia gravis pseudoparalytica. Since mental stress can be involved in the onset of the disease, it is recommended that patients who are already ill be exposed to as little mental stress as possible. As a result, at least the progression of myasthenia gravis pseudoparalytica can be contained.
In the case of a myasthenia gravis pseudoparalytica the affected person has in most cases only very few and only limited measures and possibilities of a direct follow-up available. Patients should therefore contact a doctor as early as possible so that there are no further compilations or complaints. The sooner a doctor is contacted, the better is usually the further course of the disease.
It can not come to a self-healing, with the complaints usually continue to worsen, if it does not come to a treatment. Most sufferers of myasthenia gravis pseudoparalytica depend on the use of various medications. It should always be paid to a regular intake and also on a proper dosage to relieve the symptoms and limit.
For side effects or questions, always consult a doctor first. Any changes on the skin should always be checked immediately by a doctor. Complete healing is usually not possible. Often the contact with other persons affected by myasthenia gravis pseudoparalytica makes sense, since there is an exchange of information that can make everyday life easier.
Depending on the type of muscle groups involved and the degree of muscle weakness, there are numerous ways to make everyday life easier with myasthenia gravis pseudoparalytica. The daily routine should be tailored to individual performance - it is important, above all, to schedule enough breaks. In the household tools such as opener for bottles and disposable glasses or easy-to-use kitchen appliances compensate for lack of muscle power, a stool helps tired legs. Frequently needed items are best kept in reach and not above head height, slippers with non-slip soles prevent falls on smooth floors. When driving, power steering and automatic transmission save valuable forces.
If vision is impaired by double vision, covering an eye with an eye patch or a special contact lens will help. To prevent the sight of the covered eye from decreasing continuously, the device must be used alternately on both eyes. Wearing sunglasses is recommended when eye problems occur especially in bright light.
Nicotine, caffeine and larger amounts of alcohol can temporarily increase the symptoms, and even a reaction to strong-smelling substances such as cleansers or perfume is possible. Stress and emotional stress, but also changes in the weather and infections often affect the well-being of those affected. The learning of a relaxation technique, but also an open dealing with the disease is helpful especially in worse phases.Tags: